The effects of NLR on the diagnosis and pharmacological management of brain abscesses
The effects of NLR on the diagnosis and pharmacological management of brain abscesses Çalışkan, Tezcan; Yılmaz, İbrahim; Hacıoğlu Kasım, Fatma Bahar; Ersöz, Emel; Doğan, Mustafa; Karaaslan, Numan Aim: The present study aims to examine the effectiveness of the neutrophil-tolymphocyte ratio in the treatment and diagnosis of patients with brain abscesses. Methods: In this retrospective study, radiological, neurological, and surgical data obtained from the medical records of healthy volunteers (n = 10) who presented to the hospital for check-ups and patients with brain abscesses who were treated (n = 10) were evaluated statistically. Alpha significance value was accepted as
The effects of NLR on the diagnosis and pharmacological management of brain abscesses Çalışkan, Tezcan; Yılmaz, İbrahim; Hacıoğlu Kasım, Fatma Bahar; Ersöz, Emel; Doğan, Mustafa; Karaaslan, Numan Aim: The present study aims to examine the effectiveness of the neutrophil-tolymphocyte ratio in the treatment and diagnosis of patients with brain abscesses. Methods: In this retrospective study, radiological, neurological, and surgical data obtained from the medical records of healthy volunteers (n = 10) who presented to the hospital for check-ups and patients with brain abscesses who were treated (n = 10) were evaluated statistically. Alpha significance value was accepted as <0.05. Results: Comparisons between groups revealed that the erythrocyte sedimentation rate, C-reactive protein, leukocyte, and neutrophil values were statistically significant (P <0.05) while lymphocyte value was not statistically significant (P >0.05). The preoperative neutrophil-to-lymphocyte ratio in cases diagnosed with brain abscesses showed statistical significance compared to that in the healthy volunteers (P <0.05) and the neutrophil-to-lymphocyte ratio increased 3.31-fold in the study group compared to the healthy volunteers. Conclusion: A strong positive strong relationship between the neutrophil-tolymphocyte ratio and abscess size (r = 0.662; P = 0.037) was observed. An increased neutrophil-to-lymphocyte ratio may serve as an early warning signal of brain abscesses.; Amaç: Bu makalede; beyin apsesi tanısı alan olgularda, nötrofil-lenfosit oranı (NLO)’nın, tanı ve tedavide önemli olup olmadığının incelenmesi amaçlandı. Metot: Retrospektif dizayna sahip araştırmada, hastaneye kontrol için gelen sağlıklı bireyler (n=10) ile beyin apsesi olan ve tedavi edilen olgular (n=10)’dan elde edilen radyolojik, nörolojik ve cerrahi veriler istatistiksel olarak değerlendirmeye alındı. Alfa anlamlılık değeri <0,05 olarak kabul edildi. Bulgular: Gruplar arası karşılaştırmalar sonucunda; eritrosit çökelme oranı (ESR), C-reaktif protein (CRP), lökosit (WBC) ve nötrofil (NEU) değerleri istatistiksel olarak anlamlı iken (P<0,05), lenfosit (LYMPH) değerinde istatistiksel olarak anlamlılık görülmedi (P>0,05). Sağlıklı bireylere oranla beyin apsesi tanısı alan olgulara ait preoperatif NLO değerlerinin istatistiksel olarak anlamlılık (P<0,05) gösterdiği ve NLO değerinin sağlıklı bireylere oranla yaklaşık 3,31 kat artış gösterdiği kaydedildi. Sonuç: NLO oranı ile abse boyutu arasında (r=0,662; P=0,037) pozitif yönde kuvvetli ilişki bulunmaktadır. Artış gösteren NLO, beyin apsesinin tanısında erken uyarı sinyali olarak hizmet edebilir.